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CAPRISA Microbicide Reduces Risk of HIV Infection in Women by 39%

July 30, 2010



On Monday, July 19th, 2010, researchers at the XVIII International AIDS Conference in Vienna announced that the microbicide trial carried out by the Centre for the AIDS Programme of Research in South Africa (CAPRISA), showed evidence that the vaginal microbicidal gel in question , when applied in the hours before and after sexual intercourse, reduced the risk of HIV infection in women by a male partner by 39% overall.  Such a product is desperately required, particularly in situations where women lack autonomy over sexual decision-making, including when and with whom they have sex, as well as difficulty negotiating condom use with male partners. 

Approximately half of the women included in the trial were provided with the microbicide and instructions for its use, while the other half were given a placebo.  The CAPRISA microbicide contains 1% tenofovir, which is an anti-retroviral compound currently used to treat HIV.  889 women were included in the trial, with some living in the rural South African area of Vulindlela, and some living in the urban area of Durban.


To view the published results of the trial, please follow the link below:

Science“Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women” July 19th, 2010.


For more information about the trial, please consult the following articles:


Globe and Mail- “‘Invisible Condom’ Reduces HIV Risk” By: André Picard, Monday, July 19th, 2010.


CBC News- “Anti-HIV Gel Protects Women: Study” Monday, July 19th, 2010.


Kaiser Family Foundation- “AIDS 2010: Study Finds Microbicide Containing HIV Drug Lowers Infection Risk in Women by 39%” Tuesday, July 20th, 2010.


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